Mathematical Model of Clonal Selection and Antibody Production

descriptionPublicationkeyboard_double_arrow_right Article 01 Nov 1970 English Publisher:Springer Science and Business Media LLCJournal:Nature, volume 228, pages 739-744 (issn: 0028-0836, eissn: 1476-4687,

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Authors: G I, Bell;

doi: 10.1038/228739a0 , 10.1016/0022-5193(70)90019-6 , 10.1016/0022-5193(71)90071-3

pmid: 5500468 , 4109322 , 5472961

Mathematical Model of Clonal Selection and Antibody Production

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Abstract

Equations are developed to describe the effects of interaction between antigen and target cell. The model shows promise in predicting the constants of simple experimental systems.

Related Organizations

University of Colorado System
United States
Los Alamos National Laboratory
United States

Keywords

Time Factors, Binding Sites, Computers, Models, Biological, Clone Cells, Antigen-Antibody Reactions, Antibody Formation, Immune Tolerance, Animals, Rabbits, gamma-Globulins, Antigens, Antibody-Producing Cells, Dinitrophenols

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