Immunosuppression by L-Asparaginase

descriptionPublicationkeyboard_double_arrow_right Article 01 Feb 1970 United States English Publisher:Springer Science and Business Media LLCJournal:Nature, volume 225, pages 550-552 (issn: 0028-0836, eissn: 1476-4687,

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Authors: Berenbaum, M C;

doi: 10.1038/225550a0

pmid: 4904264

Immunosuppression by L-Asparaginase

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Abstract

L-ASPAHAGINASE, an enzyme which occurs in the serum of certain rodents and is produced by various microorganisms, catalyses the hydrolysis of asparagine to L-aspartic acid and ammonia. It has been found useful in the treatment of acute lymphoblastic leukaemia and in occasional cases of other types of neoplasm in man1.

Country

United States

Related Organizations

Imperial College London
United Kingdom
Imperial College Healthcare NHS Trust
United Kingdom
St Mary's Hospital
United Kingdom
Jackson Laboratory
United States

Keywords

Serology: Antigen, Erythrocytes, Sheep, Mice, Chemotherapy:, Bacteria:, Antibody Formation, Injections, Intravenous, Escherichia coli, Animals, Asparaginase, Erwinia, Strains: BALB/C, Immunosuppressive Agents

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