Toxicity of Pyrrolizidine Alkaloids

Name: Toxicity of Pyrrolizidine Alkaloids
Creator: A R, Mattocks
Keywords: Male, Models, Structural, Alkaloids, Liver, Spectrum Analysis, Animals, Pyrroles, In Vitro Techniques, Rats, 3. Good health

A R, Mattocks

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Nature

Article . 1968 . Peer-reviewed

License: Springer TDM

Data sources: Crossref

Nature

Article . 1968

Data sources: Europe PubMed Central

https://dx.doi.org/10.1038/217...

Article

Data sources: Microsoft Academic Graph

Toxicity of Pyrrolizidine Alkaloids

descriptionPublicationkeyboard_double_arrow_right Article 01 Feb 1968 English Publisher:Springer Science and Business Media LLCJournal:Nature, volume 217, pages 723-728 (issn: 0028-0836, eissn: 1476-4687,

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Authors: A R, Mattocks;

doi: 10.1038/217723a0

pmid: 5641123

Toxicity of Pyrrolizidine Alkaloids

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Abstract

A new class of metabolite, with a pyrrole-like structure, has been demonstrated in the tissues of animals poisoned by pyrrolizidine alkaloids. There is some correlation between the degree of hepato-toxicity and the amount of “pyrrole” found in the liver. Evidence has been found of the types of reactions such metabolites might undergo with tissue constituents.

Keywords

Male, Models, Structural, Alkaloids, Liver, Spectrum Analysis, Animals, Pyrroles, In Vitro Techniques, Rats

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