Adjuvanticity of Vitamin A

descriptionPublicationkeyboard_double_arrow_right Article 01 Feb 1968 English Publisher:Springer Science and Business Media LLCJournal:Nature, volume 217, pages 527-529 (issn: 0028-0836, eissn: 1476-4687,

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Authors: D W, Dresser;

doi: 10.1038/217527a0

pmid: 4170941

Adjuvanticity of Vitamin A

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Abstract

Vitamin A may act as an adjuvant through its effect in damaging lysosomal membranes, in this way stimulating cell division. Possibly this stimulation of cell division at the time when antigen is available in the cell leads to the induction of immunity and not paralysis.

Related Organizations

National Institute for Medical Research
United Kingdom
National Institute for Medical Research
Tanzania (United Republic of)

Keywords

Male, Pertussis Vaccine, Cell Membrane, Bordetella pertussis, Mice, Adjuvants, Immunologic, Antibody Formation, Animals, Paralysis, Cattle, gamma-Globulins, Antigens, Lysosomes, Vitamin A, Cell Division

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