Induction of Tumours in Hamsters with Infectious Canine Hepatitis Virus

descriptionPublicationkeyboard_double_arrow_right Article 01 Jul 1967 English Publisher:Springer Science and Business Media LLCJournal:Nature, volume 215, pages 293-294 (issn: 0028-0836, eissn: 1476-4687,

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Authors: P S, Sarma; W, Vass; R J, Huebner; H, Igel; W T, Lane; H C, Turner;

doi: 10.1038/215293a0

pmid: 4293845

Induction of Tumours in Hamsters with Infectious Canine Hepatitis Virus

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Abstract

A NUMBER of adenoviruses which infect human beings and avian and other animal species have been shown to induce tumours in newborn golden Syrian hamsters. Included among these are several human adenoviruses1–7, chicken embryo lethal orphan (CELO) virus8, a number of simian adenoviruses9, and bovine adenovirus type 3 (ref. 10). We report here the induction of tumours in newborn hamsters by a canine adenovirus, the causative agent of infectious canine hepatitis (ICH). The tumour cells were shown to contain complement-fixing antigens for ICH virus.

Related Organizations

National Institute of Health
Pakistan
National Institutes of Health
United States

Keywords

Cricetinae, Complement Fixation Tests, Animals, Hepatovirus, Neoplasms, Experimental, Oncogenic Viruses, Neoplasm Transplantation

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