Neoplastic Transformation of Rat Embryo Cells by Simian Papovavirus SV40

descriptionPublicationkeyboard_double_arrow_right Article 01 Mar 1967 English Publisher:Springer Science and Business Media LLCJournal:Nature, volume 213, pages 931-932 (issn: 0028-0836, eissn: 1476-4687,

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Authors: A D, Altstein; N N, Vassiljeva; O F, Sarycheva;

doi: 10.1038/213931a0

pmid: 4292533

Neoplastic Transformation of Rat Embryo Cells by Simian Papovavirus SV40

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Abstract

SV40 virus manifests its oncogenic action only in hamsters1 and in mastomys2. There are, however, reports of its transformation in vitro of cells of hamsters3, mice4, rabbits4, pigs4, cows5, monkeys6 and humans7. The purpose of our investigation was to determine whether the SV40 virus possesses the ability to transform rat cells in vitro.

Keywords

Cricetinae, Culture Techniques, Muscles, Animals, Fluorescent Antibody Technique, Neoplasms, Experimental, Simian virus 40, Rats, Skin

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