
doi: 10.1038/213768a0
pmid: 4291699
Simian tumour virus SV40 induces transformation of primary cultures of cercopithecus monkey kidney cells. The cells become highly vacuolated, complement fixing viral antigen is formed and the cells become resistant to the cytopathic effects of the virus. It is probable that a persistent association develops between the cells and the virus genome.
Cytoplasm, Cytopathogenic Effect, Viral, Cricetinae, Culture Techniques, Complement Fixation Tests, Animals, Haplorhini, Simian virus 40, Antigens, Kidney, Cell Division
Cytoplasm, Cytopathogenic Effect, Viral, Cricetinae, Culture Techniques, Complement Fixation Tests, Animals, Haplorhini, Simian virus 40, Antigens, Kidney, Cell Division
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