Microbiological Transformation of Oxytetracycline

descriptionPublicationkeyboard_double_arrow_right Article 01 Aug 1966 English Publisher:Springer Science and Business Media LLCJournal:Nature, volume 211, pages 1,002-1,003 (issn: 0028-0836, eissn: 1476-4687,

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Authors: J A, Last; J F, Shell;

doi: 10.1038/2111002b0

pmid: 5338766

Microbiological Transformation of Oxytetracycline

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Abstract

THE uptake and alteration of oxytetracycline (OTC) has been demonstrated with the ascomycete Xylaria digitata1. So far as we can trace, no reports have been published concerning the fate of this drug in bacteria. Izaki and Arima2,3 have investigated the uptake and accumulation of OTC by Escherichia coli K12. They have reported that large amounts of the antibiotic are retained by the cells, but the chemical nature of the intracellular OTC was not investigated.

Related Organizations

The Ohio State University
United States

Keywords

Chromatography, Paper, Escherichia coli, Oxytetracycline

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