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Nature
Article
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Nature
Article . 1964 . Peer-reviewed
License: Springer TDM
Data sources: Crossref
Nature
Article . 1996
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Relationship between Adenoviruses and Canine Hepatitis Virus

Authors: I G, FURMINGER;

Relationship between Adenoviruses and Canine Hepatitis Virus

Abstract

IT was shown by Kapsenberg1 and Heller and Salenstedt2 that infectious canine hepatitis virus (ICH) and adenoviruses possessed common complement fixing antigens. Heller and Salenstedt2 demonstrated five precipitin lines in Ouchterlony plates in the reaction between ICH and convalescent serum from a dog infected with ICH. Three of the antigens forming these precipitin lines were common to adenovirus type 7 which itself gave five precipitin lines with human anti-adenovirus type 7 convalescent serum. The immunological relationship between the two viruses was one-sided, as anti-adenovirus type 7 serum would react in Ouchterlony plates with ICH, but anti-ICH would not react with adenovirus type 7. Recently, Darbyshire and Pereira3 have demonstrated two antigens in the livers of ICH infected dogs which can be precipitated with dog anti-ICH. One of these antigens is precipitated by rabbit anti-adenovirus type 5 serum. In the experiments reported here it was found that ICH infected dog kidney cultures produced only two soluble viral antigens, one of which is closely similar to the A (group specific) antigen of adenoviruses types 5 and 7 and another which is specific for ICH.

Keywords

Immunodiffusion, Virus Cultivation, Research, Adenoviruses, Canine, Hepatitis A, Hepatitis, Animal, Kidney, Precipitin Tests, Adenoviridae, Tissue Culture Techniques, Dogs, Hepatitis Viruses, Rabbits

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    popularity
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    influence
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
5
Average
Top 10%
Average
bronze