
doi: 10.1038/194976a0
pmid: 13888162
THE urine in patients with generalized melanoma contains substances which cause its dark colour when exposed to air—urinary melanogens1,2, of which there are two types3: (1) nitrogen melanogens, insoluble in ether or ethylacetate, giving a positive Thormahlen test4–6—indole melanogens, as they are called, and (2) non-nitrogen melanogens, soluble in ether or ethylacetate, giving a negative Thormahlen test—phenol melanogens.
Humans, Tyrosine, Melanoma
Humans, Tyrosine, Melanoma
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