The Nuclear Membrane as a Barrier to the Free Diffusion of Proteins

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1960 English Publisher:Springer Science and Business Media LLCJournal:Nature, volume 185, pages 250-251 (issn: 0028-0836, eissn: 1476-4687,

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Authors: C M, FELDHERR; A B, FELDHERR;

doi: 10.1038/185250a0

pmid: 13822019

The Nuclear Membrane as a Barrier to the Free Diffusion of Proteins

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Abstract

A RECENT investigation of the osmotic properties of the nucleus in intact frog oocytes has indicated that the nuclear membrane of these cells is not freely permeable to large molecules (mol. wt. 40,000 or greater)1. The present investigation was carried out in order to determine whether or not similar results could be obtained for oocytes of an unrelated species.

Related Organizations

King’s University
United States
Columbia University, USA
United States
University of Pennsylvania
United States

Keywords

Cell Nucleus, Diffusion, Nuclear Envelope, Humans, Proteins, Cell Physiological Phenomena

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