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Nature
Article
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Nature
Article . 1956 . Peer-reviewed
License: Springer Nature TDM
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Nature
Article . 2003
Data sources: Europe PubMed Central
https://dx.doi.org/10.1038/177...
Article
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Mode of Action of Isonicotinic Hydrazide

descriptionPublicationkeyboard_double_arrow_right Article 10 Mar 1956 English Publisher:Springer Science and Business Media LLCJournal:Nature, volume 177, pages 480-480 (issn: 0028-0836, eissn: 1476-4687, Copyright policy )
Authors: S D, RUBBO; J, EDGAR; J, CYMERMAN-CRAIG; G N, VAUGHAN; D, WILLIS;

doi: 10.1038/177480a0

pmid: 13309343

Mode of Action of Isonicotinic Hydrazide

Abstract

IN our earlier report we directed attention to the importance of chelation as an essential step in the anti-tuberculous activity of isonicotinic hydrazide (isoniazid)1. It was impossible to decide whether the chelating action with a metal or metals took place before (in the medium) or after adsorption on the bacterial cell.

Related Organizations
Keywords

Isomerism, Nicotinic Acids, Tuberculosis, Mycobacterium tuberculosis, Niacin, Anti-Bacterial Agents

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 9
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Average
Powered by OpenAIRE graph
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
9
Average
Top 10%
Average
bronze