Isolation from Argemone Oil of Dihydrosanguinarine and Sanguinarine : Toxicity of Sanguinarine

descriptionPublicationkeyboard_double_arrow_right Article 01 Aug 1948 English Publisher:Springer Science and Business Media LLCJournal:Nature, volume 162, pages 265-266 (issn: 0028-0836, eissn: 1476-4687,

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Authors: S M, SARKAR;

doi: 10.1038/162265a0

pmid: 18877104

Isolation from Argemone Oil of Dihydrosanguinarine and Sanguinarine : Toxicity of Sanguinarine

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Abstract

ARGEMONE oil has received considerable attention during recent years on account of its alleged etiological role in epidemic dropsy1-4. I pointed out5 certain anomalies of the mustard oil - argemone oil theory of epidemic dropsy and stressed the fact that a definite solution of the problem could only be arrived at by isolating the active principle from argemone oil and the suspected mustard oil, and then showing that these are chemically identical and possess similar toxic properties. Lai et al.2 could not produce any satisfactory evidence on this aspect of the problem.

Keywords

Benzophenanthridines, Humans, Plant Oils, Isoquinolines

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