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image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
Nature
Article . 1946 . Peer-reviewed
License: Springer TDM
Data sources: Crossref
Nature
Article . 2010
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Botanical Origin of Tube-Curare

Authors: H, KING;

Botanical Origin of Tube-Curare

Abstract

dextro-Tubocurarine chloride was first isolated in crystalline form from native tube-curare1. It has since become a valuable adjunct in anaesthesia2. The chemical constitution of dextro-tubocurine chloride and its relation to bebeerine3 suggests that its botanical origin lies in some species of Chondrodendron. Through the kindness of Mr. J. W. Massey, British consul in Iquitos, the stem and leaves of Chondrodendron tomentosum Ruiz and Pavon, collected by the late Guillermo Klug at Tarapoto in Peru, have been made available. The leaves were identified by Mr. N. Y. Sandwith of the Herbarium, Kew, as belonging to this species, and on chemical examination the stems yielded l"vo-curine (l-bebeerine) and l"vo-tubocurarine chloride. The latter was found by Dr. B. D. Burns to have a curare action on the rat's diaphragm, which was very weak when compared with that of dextro-tubocurarine chloride.

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Keywords

Humans, Curare

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
10
Average
Top 10%
Average
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