IN connexion with part of the recent note of Beattie and Marshall1, which may give the impression that methionine has a strikingly beneficial effect upon patients suffering from so-called "post-arsphenamine" jaundice, we feel that the time has arrived to report very briefly some of our own results in a trial on similar lines started by us more than a year ago. Promise of its success was indicated by the literature; and it was felt that every therapeutic possibility should be explored in view of the high incidence of this serious complication.