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Nature Genetics
Article . 1999 . Peer-reviewed
License: Springer TDM
Data sources: Crossref
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Visualisation and analysis of gene expression data

Authors: P Kalocsai;

Visualisation and analysis of gene expression data

Abstract

P roducing microarray data starts with scanning in the glass, gel or plastic slides with a specialized scanner to obtain digital images of the results of an experiment after hybridization. With the help of image analysis software the DNA expression levels are then quantified. After the image processing and analysis step is completed we end up with a large number of quantified gene expression values. The data typically represents hundreds or thousands, in certain cases tens of thousands, of gene expressions across multiple experiments. To make sense of this much information it is unavoidable to use various visualization and statistical analysis techniques. One of the most typical microarray data analysis goals is to find statistically significant up or down regulated genes, in other words outliers or ‘interestingly’ behaving genes in the data. Other possible goals could be to find functional groupings of genes by discovering similarity or dissimilarity among gene expression profiles, or predicting the biochemical and physiological pathways of previously uncharacterized genes.

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    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    3
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Average
Powered by OpenAIRE graph
Found an issue? Give us feedback
selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
3
Average
Average
Average
bronze