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Overview of Voltage-Dependent Calcium Channels

Name: Overview of Voltage-Dependent Calcium Channels
Creator: Stephen W. Jones
Keywords: 0301 basic medicine, Models, Molecular, 0303 health sciences, Protein Conformation, Muscle Proteins, Nerve Tissue Proteins, Membrane Potentials, 3. Good health, 03 medical and health sciences, GTP-Binding Proteins

descriptionPublicationkeyboard_double_arrow_right Article 01 Aug 1998Publisher:Springer Science and Business Media LLCJournal:Journal of Bioenergetics and Biomembranes, volume 30, pages 299-312 (issn: 0145-479X, eissn: 1573-6881,

Authors: Stephen W. Jones;

doi: 10.1023/a:1021977304001

pmid: 9758327

Overview of Voltage-Dependent Calcium Channels

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Abstract

Voltage-dependent calcium channels couple electrical signals to cellular responses in excitable cells. Calcium channels are crucial for excitation-secretion coupling in neurons and endocrine cells, and excitation-contraction coupling in muscle. Several pharmacologically and kinetically distinct calcium channel types have been identified at the electrophysiological and molecular levels. This review summarizes the basic properties of voltage-dependent calcium channels, including mechanisms of ion permeation and block, gating kinetics, and modulation by G proteins and second messengers.

Related Organizations

Case Western Reserve University
United States

Keywords

Models, Molecular, Protein Conformation, Muscle Proteins, Nerve Tissue Proteins, Membrane Potentials, GTP-Binding Proteins, Multigene Family, Animals, Humans, Calcium, Calcium Channels, Calcium Signaling, Ion Channel Gating

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	126
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	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%