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Journal of Proteome Research
Article . 2010 . Peer-reviewed
Data sources: Crossref
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Insight into the Sialome of the Bed Bug,Cimex lectularius

Authors: Ivo M B, Francischetti; Eric, Calvo; John F, Andersen; Van M, Pham; Amanda J, Favreau; Kent D, Barbian; Alvaro, Romero; +2 Authors

Insight into the Sialome of the Bed Bug,Cimex lectularius

Abstract

The evolution of insects to a blood diet leads to the development of a saliva that antagonizes their hosts' hemostasis and inflammation. Hemostasis and inflammation are redundant processes, and thus a complex salivary potion composed of dozens or near 100 different polypeptides is commonly found by transcriptome or proteome analysis of these organisms. Several insect orders or families evolved independently to hematophagy, creating unique salivary potions in the form of novel pharmacological use of endogenous substances and in the form of unique proteins not matching other known proteins, these probably arriving by fast evolution of salivary proteins as they evade their hosts' immune response. In this work we present a preliminary description of the sialome (from the Greek Sialo = saliva) of the common bed bug Cimex lectularius, the first such work from a member of the Cimicidae family. This manuscript is a guide for the supplemental database files http://exon.niaid.nih.gov/transcriptome/C_lectularius/S1/Cimex-S1.zip and http://exon.niaid.nih.gov/transcriptome/C_lectularius/S2/Cimex-S2.xls.

Keywords

Male, Models, Molecular, Proteomics, Bedbugs, Base Sequence, Molecular Sequence Data, Computational Biology, Feeding Behavior, Sequence Analysis, DNA, Enzymes, Acetylcholinesterase, Animals, Insect Proteins, Female, Amino Acid Sequence, Salivary Proteins and Peptides, Sequence Alignment, Phylogeny, DNA Primers, Gene Library

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
64
Top 10%
Top 10%
Top 10%
bronze