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Synthesis of a Bistetrahydrofuran C17−C32 Fragment of the Polyether Antibiotic Ionomycin

descriptionPublicationkeyboard_double_arrow_right Article 01 Sep 2006 English Publisher:American Chemical Society (ACS)Journal:Organic Letters, volume 8, pages 4,375-4,378 (issn: 1523-7060, eissn: 1523-7052, Copyright policy )
Authors: James A. Marshall; Ann M. Mikowski;

doi: 10.1021/ol061826u

pmid: 16956230

Synthesis of a Bistetrahydrofuran C17−C32 Fragment of the Polyether Antibiotic Ionomycin

Abstract

A Zn-initiated triepoxide cascade cyclization reaction was employed for the synthesis of the bistetrahydrofuran core segment of the polyether ionophore antibiotic ionomycin.

Related Organizations
Keywords

Ionomycin, Stereoisomerism, Furans, Anti-Bacterial Agents

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    citations
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    		 29
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
29
Average
Average
Top 10%
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