Tyrosinase Inhibitors from Anacardium occidentale Fruits
Copyright policy )Tyrosinase Inhibitors from Anacardium occidentale Fruits
Anacardic acids, 2-methylcardols, and cardols isolated from various parts of the cashew [Anacardium occidentale] (Anacardiaceae) fruit have been found to exhibit tyrosinase inhibitory activity. Kinetic studies with the two principal active compounds, 6-[8(Z),11(Z),14-pentadecatrienyl]salicylic acid and 5-[8(Z),11(Z),14-pentadecatrienyl]resorcinol, have indicated that both of these phenolic compounds exhibit characteristic competitive inhibition of the oxidation of L-3,4-dihydroxyphenylalanine (L-DOPA) by mushroom tyrosinase.
- University of California, Berkeley United States
Monophenol Monooxygenase, Basidiomycota, Resorcinols, Salicylates, Anacardic Acids, Levodopa, Kinetics, Structure-Activity Relationship, Nuts, Oxidation-Reduction
Monophenol Monooxygenase, Basidiomycota, Resorcinols, Salicylates, Anacardic Acids, Levodopa, Kinetics, Structure-Activity Relationship, Nuts, Oxidation-Reduction
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