From an MeOH extract of the stems of Premna corymbosa var. obtusifolia,thirteen compounds were isolated. The structure of a new compound 1 was determined to be 3-hydroxy-4-methoxyphenethyl alcohol β-D-(3'-O-α-L-rhamnopyranosyl,-4'-O-β-D-glucopyranosyl,-6'-O-feruloyl) glucopyranoside. Confirmation of the stereochemical structure of 4-epi-gummadiol-4-O-β-D-glucopyranoside [6] was also performed in this study