Withanolides from Salpichroa origanifolia

descriptionPublicationkeyboard_double_arrow_right Article 01 Jun 2001 English Publisher:American Chemical Society (ACS)Journal:Journal of Natural Products, volume 64, pages 783-786 (issn: 0163-3864, eissn: 1520-6025,

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Authors: M C, Tettamanzi; A S, Veleiro; J R, de la Fuente; G, Burton;

doi: 10.1021/np010010t

pmid: 11421743

Withanolides from Salpichroa origanifolia

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Abstract

Five new withanolides, 5 alpha,6 alpha:22,26:24,25-triepoxy-16 alpha,26-dihydroxy-18(13-->17)-abeo-ergosta-2,13-dien-1-one (salpichrolide N, 1), 5 alpha,6 alpha:22,26:24,25-triepoxi-15 alpha,26-dihydroxyergosta-2,16-dien-1-one (salpichrolide L, 2), 5 alpha,6 alpha:22,26-diepoxi-24,25,26-trihydroxy-17(13-->18)-abeo-ergosta-2,13,15,17-tetraen-1-one (salpichrolide M, 3a), 5 alpha,6 alpha:22,25:22,26-triepoxy-24-hydroxy-17(13-->18)-abeo-ergosta-2,13,15,17-tetraen-1-one (salpichrolide J, 4), and 5 alpha,6 alpha:22,26-diepoxy-22,24,25-trihydroxy-17(13-->18)-abeo-ergosta-2,13,15,17-tetraen-1-one (salpichrolide K, 5), were isolated from the leaves of Salpichroa origanifolia and characterized by a combination of spectroscopic (1D and 2D NMR, MS) and chemical methods.

Related Organizations

University of Buenos Aires
Argentina
Facultad de Ciencias Agrarias y Forestales
Argentina
National University of Salta
Argentina

Keywords

Magnetic Resonance Spectroscopy, Plants, Medicinal, Ergosterol, Argentina, Mass Spectrometry

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