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Archivio Istituzionale della Ricerca dell'Università degli Studi di Milano
Article . 2006
Data sources: Archivio Istituzionale della Ricerca dell'Università degli Studi di Milano
The Journal of Organic Chemistry
Article . 2006 . Peer-reviewed
Data sources: Crossref
The Journal of Organic Chemistry
Article . 2007
Data sources: Europe PubMed Central
CNR ExploRA
Article . 2006
Data sources: CNR ExploRA
https://dx.doi.org/10.1021/jo0...
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Synthesis of (+)-Spirolaxine Methyl Ether

descriptionPublicationkeyboard_double_arrow_right Article 11 Jul 2006 Italy English Publisher:American Chemical Society (ACS)Journal:The Journal of Organic Chemistry, volume 71, pages 6,277-6,280 (issn: 0022-3263, eissn: 1520-6904, Copyright policy )
Authors: R.NANNEI; S.DALLAVALLE; A. BAVA; G. NASINI; L. MERLINI;

doi: 10.1021/jo060839i

pmid: 16872220

handle: 2434/26581

Synthesis of (+)-Spirolaxine Methyl Ether

Abstract

A short and efficient synthesis of (+)-spirolaxine methyl ether, a metabolite of the fungus Sporotrichum laxum with inhibitory activity against Helicobacter pylori, is described. The synthesis has been carried out by a Prins cyclization, to obtain the [6,5]-spiroketal system, and a Wadsworth-Emmons condensation, applied for the installation of the polymethylene chain on the phthalide moiety.

Country
Italy
Related Organizations
Keywords

Magnetic Resonance Spectroscopy, Molecular Structure, Spirolaxine; asymmetric synthesis, Spiro Compounds

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
42
Top 10%
Top 10%
Top 10%
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