
A time-intensity gas chromatography-olfactometry (GCO) apparatus was developed to study some aerodynamic parameters that may influence odor detection and intensity measurements by the subjects. The addition of humidified air at the elution place of the compounds is generally recommended for several reasons (essentially to prevent nasal mucosa dehydration and to improve chromatographic effluent carriage out of the column), but clues about these effects are yet to be published. This question is studied through two complementary experiments using synthetic solutions of 3-methyl-1-butanethiol, hexan-2-one, octanal, nonanal, furfural, citronellal, benzaldehyde, octan-1-ol, 2-phenylethyl acetate, guaiacol, 2-phenylethanol, and vanillin. This work demonstrates the need for an air makeup to increase odor detection frequency and intensity rating. With the conditions tested, a minimum makeup air flow rate of 50 L.min(-)(1) is necessary. On the contrary, humidification of the makeup is useless for the sniffers comfort and to improve the quantitative GCO results.
Adult, Male, Smell, Aldehydes, Nasal Mucosa, Chromatography, Gas, Air, Alcohols, Odorants, Humans, Female
Adult, Male, Smell, Aldehydes, Nasal Mucosa, Chromatography, Gas, Air, Alcohols, Odorants, Humans, Female
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