Deoxyribozyme-Based Logic Gates
Copyright policy )Deoxyribozyme-Based Logic Gates
We report herein a set of deoxyribozyme-based logic gates capable of generating any Boolean function. We construct basic NOT and AND gates, followed by the more complex XOR gate. These gates were constructed through a modular design that combines molecular beacon stem-loops with hammerhead-type deoxyribozymes. Importantly, as the gates have oligonucleotides as both inputs and output, they open the possibility of communication between various computation elements in solution. The operation of these gates is conveniently connected to a fluorescent readout.
- King’s University United States
- University of New Mexico United States
Base Sequence, Logic, Drug Design, Molecular Sequence Data, Oligonucleotides, Nucleic Acid Conformation, Biosensing Techniques, DNA, Catalytic
Base Sequence, Logic, Drug Design, Molecular Sequence Data, Oligonucleotides, Nucleic Acid Conformation, Biosensing Techniques, DNA, Catalytic
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