Exploring the Intermembrane Space
Copyright policy )Exploring the Intermembrane Space
Despite the importance that many components of the intermembrane space (IMS) of mitochondria play in cellular function, the targeting sequences that are responsible for transporting proteins to this subcellular compartment are not fully understood. A recent study has identified a minimized protein sequence that is sufficient for localizing the apoptogenic protein Smac/DIABLO in the IMS. This newly identified targeting sequence is capable of directing other proteins to this submitochondrial compartment as well.
- Washington State University United States
- University of Mary United States
Mitochondrial Proteins, Green Fluorescent Proteins, Mitochondrial Membranes, Intracellular Signaling Peptides and Proteins, Humans, Apoptosis Regulatory Proteins, DNA Polymerase III
Mitochondrial Proteins, Green Fluorescent Proteins, Mitochondrial Membranes, Intracellular Signaling Peptides and Proteins, Humans, Apoptosis Regulatory Proteins, DNA Polymerase III
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