Abstract Non-Technical Summary Plastic harms ecosystem health and human livelihood on land, in rivers, and in the sea. To prevent and reduce plastic pollution, we must know how plastics move through the environment. Extreme events, such as floods, bring large amounts of plastic into rivers around the world. This article summarizes how different flood types (excessive rainfall, high river flow, or floods from the sea) flush or deposit plastic pollution, and how this impacts the environment. Furthermore, this paper also discusses how improved resilience to floods is important to prevent and reduce plastic pollution. Technical Summary Plastic pollution is ubiquitous in the environment and threatens terrestrial, freshwater, and marine ecosystems. Reducing plastic pollution requires a thorough understanding of its sources, sinks, abundance, and impact. The transport and retention dynamics of plastics are however complex, and assumed to be driven by natural factors, anthropogenic factors, and plastic item characteristics. Current literature shows diverging correlations between river discharge, wind speed, rainfall, and plastic transport. However, floods have been consistently demonstrated to impact plastic transport and dispersal. This paper presents a synthesis of the impact of floods on plastic pollution in the environment. For each specific flood type (fluvial, pluvial, coastal, and flash floods), we identified the driving transport mechanisms from the available literature. This paper introduces the plastic-flood nexus concept, which is the negative feedback loop between floods (mobilizing plastics), and plastic pollution (increasing flood risk through blockages). Moreover, the impact of flood-driven plastic transport was assessed, and it was argued that increasing flood resilience also reduces the impact of floods on plastic pollution. This paper provides a perspective on the importance of floods on global plastic pollution. Increasing flood resilience and breaking the plastic-flood nexus are crucial steps toward reducing environmental plastic pollution. Social Media Summary Floods have a large impact on plastic pollution transport, which can be reduced through improved flood resilience