Pathway rewiring with neural transplantation

descriptionPublicationkeyboard_double_arrow_right Article 01 Mar 1995 English Publisher:Cambridge University Press (CUP)Journal:Behavioral and Brain Sciences, volume 18, pages 73-73 (issn: 0140-525X, eissn: 1469-1825,

Authors: Piergiorgio Strata; Ferdinando Rossi;

doi: 10.1017/s0140525x00037535

Pathway rewiring with neural transplantation

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Abstract

AbstractA lesion to the brain is not necessary for a successful neural transplantation. Embryonic Purkinje cells placed on the surface of an uninjured adult cerebellum can develop and migrate into the host molecular layer. Both the Purkinje cells that migrated into the host cerebellum and those that remained in the graft were innervated by collateral sprouting of adult intact climbing fibers.

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University of Turin
Italy

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