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Molecular Cell
Article
License: Elsevier Non-Commercial
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Molecular Cell
Article . 2003
License: Elsevier Non-Commercial
Data sources: BASE (Open Access Aggregator)
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Molecular Cell
Article . 2003 . Peer-reviewed
License: Elsevier Non-Commercial
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Molecular Cell
Article . 2004
Data sources: Europe PubMed Central
Molecular Cell
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The Missing Linker

descriptionPublicationkeyboard_double_arrow_right Article 01 Dec 2003 English Publisher:Elsevier BVJournal:Molecular Cell, volume 12, pages 1,349-1,351 (issn: 1097-2765, Copyright policy )
Authors: Ron R. Kopito;

doi: 10.1016/s1097-2765(03)00498-2

pmid: 14690590

The Missing Linker

Abstract

Molecular motors are the long-haul carriers of eukaryotic cells, moving cargos bidirectionally along microtubule tracks. In the December 12th issue of Cell, report that HDAC6, a tubulin deacetylase, functions as an adaptor that links cargos of aggregated protein to the minus end-directed motor, cytoplasmic dynein.

Related Organizations
Keywords

Proteasome Endopeptidase Complex, Protein Folding, Ubiquitin, Molecular Motor Proteins, Dyneins, Biological Transport, Cell Biology, Dynactin Complex, Histone Deacetylase 6, Histone Deacetylases, Cysteine Endopeptidases, Multienzyme Complexes, Molecular Biology, Microtubule-Associated Proteins

  • BIP!
    Impact byBIP!
    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 21
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 10%
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
21
Top 10%
Average
Top 10%
hybrid