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Developmental Evolution: Getting Robust About Robustness

descriptionPublicationkeyboard_double_arrow_right Article 01 May 2002 English Publisher:Elsevier BVJournal:Current Biology, volume 12, pages R347-R349 (issn: 0960-9822, Copyright policy )
Authors: Gibson, Greg;

doi: 10.1016/s0960-9822(02)00855-2

pmid: 12015133

Developmental Evolution: Getting Robust About Robustness

Abstract

In the context of development, a process is robust if it can proceed normally despite the enormous capacity for perturbation inherent in all biological systems. A new mode of theoretical modeling of genetic networks holds great promise for increasing our understanding of both the quantitative mechanisms of robustness and its evolutionary impact.

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Keywords

Neurons, Agricultural and Biological Sciences(all), Biochemistry, Genetics and Molecular Biology(all), Models, Neurological, Proteins, Cell Differentiation, 0601 Biochemistry and Cell Biology, Biological Evolution, Repressor Proteins, Drosophila melanogaster, Animals, Homeostasis, Nerve Net, Selection, Genetic, Biology

  • BIP!
    Impact byBIP!
    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 26
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 10%
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
26
Average
Top 10%
Top 10%
hybrid