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Chromosome cohesion: A polymerase for chromosome bridges

Name: Chromosome cohesion: A polymerase for chromosome bridges
Creator: Frank Uhlmann
Keywords: DNA Replication, 0301 basic medicine, 0303 health sciences, 03 medical and health sciences, Agricultural and Biological Sciences(all), Biochemistry, Genetics and Molecular Biology(all), DNA-Directed DNA Polymerase, Chromatids, Chromosomes, 3. Good health

descriptionPublicationkeyboard_double_arrow_right Article 01 Oct 2000Publisher:Elsevier BVJournal:Current Biology, volume 10, pages R698-R700 (issn: 0960-9822,

Authors: Frank Uhlmann;

doi: 10.1016/s0960-9822(00)00709-0

pmid: 11050403

Chromosome cohesion: A polymerase for chromosome bridges

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Abstract

How do cells ensure that sister chromatids produced during DNA replication stay connected with each other until their separation in anaphase? New insight is provided by the discovery of DNA polymerase kappa, which has been found to be required for building the connections between sister chromatids.

Related Organizations

Lincoln's Inn
United Kingdom

Keywords

DNA Replication, Agricultural and Biological Sciences(all), Biochemistry, Genetics and Molecular Biology(all), DNA-Directed DNA Polymerase, Chromatids, Chromosomes

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