The proteasome
Copyright policy )The proteasome
The proteasome is a macromolecular assembly that is designed to confine proteolytic activity to an inner cavity. Access to the central proteolytic nanocompartment is restricted to unfolded proteins, which necessitates a functional coupling of the 20S proteasome to a substrate-recognition and unfolding machinery. Significant progress has been made during the past two years in elucidating the structural principles and the enzymatic mechanism of the 20S proteasome.
- Max Planck Society Germany
- Max Planck Institute of Biochemistry Germany
Models, Molecular, Cysteine Endopeptidases, Microscopy, Electron, Proteasome Endopeptidase Complex, Multienzyme Complexes, Thermoplasma, Protein Structure, Secondary, Protein Structure, Tertiary
Models, Molecular, Cysteine Endopeptidases, Microscopy, Electron, Proteasome Endopeptidase Complex, Multienzyme Complexes, Thermoplasma, Protein Structure, Secondary, Protein Structure, Tertiary
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