
Toll-like receptors (TLRs) are essential in the host defense against microbial pathogens. Individual TLRs recognize distinct structural components of pathogens and evoke inflammatory responses. Recent evidence indicates that TLRs recognize not only bacteria and fungi but also viruses. The molecular mechanisms by which TLRs induce differential gene expression are now beginning to be clarified.
Membrane Glycoproteins, Gene Expression Regulation, Antigens, Surface, Toll-Like Receptors, Animals, Receptors, Cell Surface, Bacterial Infections, Cell Communication, Immunity, Innate, Signal Transduction
Membrane Glycoproteins, Gene Expression Regulation, Antigens, Surface, Toll-Like Receptors, Animals, Receptors, Cell Surface, Bacterial Infections, Cell Communication, Immunity, Innate, Signal Transduction
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