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pmid: 9421707
Drug-resistant tuberculosis remains a worldwide problem. New laboratory methods have improved our ability to more rapidly identify resistant strains, but the most effective approach is to prevent the appearance of resistance by appropriate choice of antibiotics and directly-observed therapy. Mycobacterium tuberculosis is treated with familiar and unique drugs; consequently, mechanisms of resistance have some unique features. All drug resistance thus far identified develops by mutational events rather than acquisition of resistance genes from other bacteria. An agenda is presented for countering the appearance of further drug resistance in mycobacteria.
Antitubercular Agents, Drug Resistance, Microbial, Microbial Sensitivity Tests, Mycobacterium tuberculosis, United States, Anti-Bacterial Agents, Cell Wall, Communicable Disease Control, Mutation, Humans, Tuberculosis, Centers for Disease Control and Prevention, U.S., Antibiotics, Antitubercular, Public Health Administration
Antitubercular Agents, Drug Resistance, Microbial, Microbial Sensitivity Tests, Mycobacterium tuberculosis, United States, Anti-Bacterial Agents, Cell Wall, Communicable Disease Control, Mutation, Humans, Tuberculosis, Centers for Disease Control and Prevention, U.S., Antibiotics, Antitubercular, Public Health Administration
citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | 38 | |
popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network. | Top 10% | |
influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | Top 10% | |
impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network. | Top 10% |