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Lipid Mediators of Inflammation

Name: Lipid Mediators of Inflammation
Creator: Dwight R. Robinson
Keywords: Inflammation, 0301 basic medicine, 0303 health sciences, 03 medical and health sciences, 0302 clinical medicine, Prostaglandins, Humans, SRS-A, Lipid Metabolism, Leukotriene B4

descriptionPublicationkeyboard_double_arrow_right Article 01 Aug 1987Publisher:Elsevier BVJournal:Rheumatic Disease Clinics of North America, volume 13, pages 385-405 (issn: 0889-857X,

Authors: Dwight R. Robinson;

doi: 10.1016/s0889-857x(21)00854-1

pmid: 2827247

Lipid Mediators of Inflammation

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Abstract

Many mediators of inflammation are derived from phospholipids and polyunsaturated fatty acids, including prostaglandins, leukotrienes, and platelet-activating factor. These mediators augment the vascular phase of inflammation and modify functions of inflammatory cells and cells of the immune system. Several growth factors or cytokines augment production of prostaglandin synthesis. The production of lipid-derived mediators may be inhibited by anti-inflammatory drugs and by modifying dietary polyunsaturated fatty acids.

Related Organizations

Harvard University
United States
Massachusetts General Hospital
United States

Keywords

Inflammation, Prostaglandins, Humans, SRS-A, Lipid Metabolism, Leukotriene B4, Lipids

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	21
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Average
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%