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Circulating HBsAg/IgM complexes in chronic HBsAg carriers

descriptionPublicationkeyboard_double_arrow_right Article 01 Oct 1983Publisher:Elsevier BVJournal:Annales de l'Institut Pasteur / Virologie, volume 134, pages 569-572 (issn: 0769-2617,

Authors: J.L. Barres; Coursaget P; B. Yvonnet; J.E. Bocande; I. Diop-Mar; Chiron Jp; E. Petat; +1 Authors

doi: 10.1016/s0769-2617(83)80029-x

Circulating HBsAg/IgM complexes in chronic HBsAg carriers

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Abstract

Summary Sera of young male HBsAg carriers from Senegal were investigated for complexes between IgM and HBsAg. An enzyme-linked immunosorbent assay based on selective absorption of IgM was used. HBsAg/IgM complexes were detected in 14% of the HBsAg carriers. They were detected in 5.0% of anti-HBe-positive sera and in 53.6% of HBeAg-positive sera. Moreover, they were present more often (37.5%) in individuals who evidenced abnormal alphafœtoprotein (AFP) levels (>15 ng/ml) than in those who had normal AFP levels (12.5%).

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