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Dystrophin in control and mdx retina

descriptionPublicationkeyboard_double_arrow_right Article 01 Mar 1991 English Publisher:Elsevier BVJournal:Brain and Development, volume 13, pages 135-137 (issn: 0387-7604,

Authors: Makoto Uchino; Teruhisa Miike; Masahiko Miyatake; Kowashi Yoshioka; Ji-en Zhao;

doi: 10.1016/s0387-7604(12)80123-9

pmid: 1892220

Dystrophin in control and mdx retina

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Abstract

To determine whether or not dystrophin really exists in the outer plexiform layer (OPL) of the retina, we studied control and mdx mice, using four kinds of polyclonal antibodies (DMDP-II, 60 kd, 30 kd and DMDP-IV) against dystrophin. Although control OPL showed a positive immunohistochemical reaction with all four antibodies, mdx OPL showed a positive reaction with DMDP-II and DMDP-IV, a negative reaction with 60 kd and 30 kd antibodies. Immunoblot analysis showed the positive band compatible with the immunohistochemical reaction.

Related Organizations

Kumamoto University
Japan

Keywords

Dystrophin, Mice, Mice, Neurologic Mutants, Immunoblotting, Animals, Fluorescent Antibody Technique, Muscular Dystrophy, Animal, Retina

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	28
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Average
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%