descriptionPublicationkeyboard_double_arrow_right Article 01 Sep 1980 English Publisher:Elsevier BVJournal:Journal of the American Academy of Dermatology, volume 3, pages 237-240 (issn: 0190-9622,

Authors: Arnold L. Schroeter; Karen Kronman Hoefling;

doi: 10.1016/s0190-9622(80)80184-8

pmid: 7451689

Dermatoimmunopathology of scabies

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Abstract

Direct immunofluorescence of scabies lesions revealed IgM, IgA, C3, and fibrin in the cornified layer of the epidermis, dermoepidermal junction, and papillary dermal vessels. The granular deposits of IgM and IgG in the dermoepidermal junction had a pattern similar to that found in lupus erythematosus. These findings support a humoral immune response secondary to scabetic infestation.

Related Organizations

Mayo Clinic
United States

Keywords

Scabies, Immunoglobulin M, Biopsy, Immunoglobulin G, Antibody Formation, Humans, Complement C3, Immunoglobulin A

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