descriptionPublicationkeyboard_double_arrow_right Article 01 Apr 1970 English Publisher:Elsevier BVJournal:The Lancet, volume 295, pages 832-833 (issn: 0140-6736,

Authors: M J, Baumblatt; F, Winston;

doi: 10.1016/s0140-6736(70)92426-8

pmid: 4191448

PYRIDOXINE AND THE PILL

- Summary
- Subjects
- Metrics

Abstract

58 women who complained of irritability (58) depression (58) fatigue (48) mild paranoid ideation (29) or poor concentration or sleep disturbance (20) while using oral contraceptives were selected for a trial of pyridoxine. They were taking Ortho-Novum 180 Ovulen 21 or Ovral and no tranquilizers or depressants for 2 to 37 months. Pyridoxine (vitamin B6) at a dose of 50 mg daily resolved symptoms completely in 18 patients considerably improved 26 and had no effect on 14. Improvement if it occurred was usually observed in hours or by the next day.

Keywords

Adult, Sleep Wake Disorders, Depression, Emotions, Tryptophan, Pyridoxine, Lynestrenol, Ethynodiol Diacetate, Pregnancy, Humans, Female, Vitamin B 6 Deficiency, Fatigue, Contraceptives, Oral

Impact byBIP!

	selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	69
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Average
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%