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Vasopressin metabolites: A link between vasopressin and memory?

descriptionPublicationkeyboard_double_arrow_right Part of book or chapter of book , Article 01 Jan 1999Publisher:Elsevier BV

Authors: Leon G.J.E. Reijmers; J. Peterr Burbach; David de Wied; Berry M. Spraijt; Jan M. van Ree;

doi: 10.1016/s0079-6123(08)61591-5

pmid: 10074810

Vasopressin metabolites: A link between vasopressin and memory?

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Abstract

The effects of endogenous metabolites of the neuropeptide vasopressin (VP) in behavioural tests led to the hypothesis that VP metabolites have a more selective function than VP. In contrast to VP, no peripheral effects have been found thus far with VP metabolites and their function seems to be associated with memory-related behaviour. VP metabolites can improve both consolidation and retrieval of memory. Effects on autonomic and electrophysiological parameters and interactions with other neurotransmitter systems have provided some information about the processes that could underlie the effects of VP metabolites on memory-related behaviour. There is evidence that the effects of VP metabolites could be mediated by a VP metabolite receptor, which is different from the known VP receptors. The VP metabolite receptor could be a link between the neuropeptide VP and memory-related behaviour.

Related Organizations

Utrecht University
Netherlands

Keywords

Arginine Vasopressin, Brain Chemistry, Memory, Animals, Brain, Maze Learning, Peptide Fragments

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