With the institution of the new chemical regulatory framework in 2003, chemicals at the workplace have been classified into five categories; banned substances, permission-required substances, regulated substances, occupational exposure limit set substances, and other generally controlled substances. Currently, there are 698 substances with OELs. As we have come to gain our own experiences in the study and control of chemical hazards at the workplace such as the 2-bromopropane poisoning, OEL setting process has been streamlined. The OELs in Korea, however, remain merely as a recommendation, which does not require all the substances with OELs to be measured at the workplace. Coordination of whole program for hazardous chemicals including workplace measurement, OEL setting process, and enforcement activities is still needed in Korea.