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Identification of a novel virus in pigs—Bungowannah virus: A possible new species of pestivirus

descriptionPublicationkeyboard_double_arrow_right Article 01 Oct 2007Publisher:Elsevier BVJournal:Virus Research, volume 129, pages 26-34 (issn: 0168-1702,

Authors: K.R. King; Melinda J Frost; Deborah S. Finlaison; Peter D. Kirkland; Julia F. Ridpath; Xingnian Gu;

doi: 10.1016/j.virusres.2007.05.002

pmid: 17561301

Identification of a novel virus in pigs—Bungowannah virus: A possible new species of pestivirus

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Abstract

In 2003 an outbreak of sudden deaths occurred in 3-4-week-old piglets on a farm in New South Wales, Australia. There was a marked increase in the birth of stillborn foetuses. Pathological changes consisted of a multifocal non-suppurative myocarditis. A viral infection was suspected but a wide range of known agents were excluded. A modified sequence independent single primer amplification (SISPA) method was used to identify a novel virus associated with this outbreak. Conserved 5'UTR motifs, the presence of a putative N(pro) coding region and limited antigenic cross-reactivity with other members of the Pestivirus genus, support the placement of this virus in the Pestivirus genus. Phylogenetic analysis of the 5'UTR, N(pro) and E2 coding regions showed this virus to be the most divergent pestivirus identified to date.

Related Organizations

United States Department of the Interior
United States
National Animal Disease Center
United States
United States Department of Agriculture
United States

Keywords

Swine Diseases, Sus scrofa, Australia, Pestivirus Infections, Weaning, Cross Reactions, Disease Outbreaks, Myocarditis, Open Reading Frames, Viral Proteins, Ribonucleases, Heparin Lyase, Viral Envelope Proteins, Endopeptidases, Pestivirus, Animals, 5' Untranslated Regions, Antigens, Viral

7 Research products, page 1 of 1

Porcine pestivirus isolate Bungowannah NPRO (NPRO) gene, partial cds.
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DQ901402
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E2
2017IsRelatedTo
Porcine pestivirus isolate Bungowannah partial E2
2018IsRelatedTo
NPRO
2017IsRelatedTo
Porcine pestivirus isolate Bungowannah partial NPRO
2018IsRelatedTo
Porcine pestivirus isolate Bungowannah E2 (E2) gene, partial cds.
2018IsRelatedTo

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