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Virology
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License: Elsevier Non-Commercial
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Virology
Article . 2018 . Peer-reviewed
License: Elsevier Non-Commercial
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Virology
Article . 2019
Data sources: Europe PubMed Central
https://dx.doi.org/10.1016/j.v...
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Isolation and characterization of H5Nx highly pathogenic avian influenza viruses of clade 2.3.4.4 in Russia

descriptionPublicationkeyboard_double_arrow_right Article 01 Dec 2018 English Publisher:Elsevier BVJournal:Virology, volume 525, pages 216-223 (issn: 0042-6822, Copyright policy )
Authors: V. Marchenko; N. Goncharova; I. Susloparov; N. Kolosova; A. Gudymo; S. Svyatchenko; A. Danilenko; +4 Authors

doi: 10.1016/j.virol.2018.09.024

pmid: 30296682

Isolation and characterization of H5Nx highly pathogenic avian influenza viruses of clade 2.3.4.4 in Russia

Abstract

In 2016-2017, several subtypes of the highly pathogenic avian influenza (HPAI) virus were isolated on the territory of Russia. In the autumn of 2016, during the avian influenza virus surveillance in the territory of the Kamchatka region of Russia the HPAI A(H5N5) influenza virus was isolated. Then, during 2016-2017, multiple outbreaks among wild birds and poultry caused by HPAI A(H5N8) avian influenza virus were recorded in European part of Russia. At the end of 2017, an outbreak among poultry caused by HPAI A(H5N2) influenza virus was recorded in the European part of Russia. Phylogenetic analysis of HA of the A(H5N5), A(H5N8), A(H5N2) showed the strains belong to the clade 2.3.4.4 b. All isolated strains were antigenically closely related to candidate vaccine viruses of clade 2.3.4.4 and showed high virulence in mice. Genetic analysis revealed presence of genetic markers potentially related to high virulence in mice in all studied viruses.

Related Organizations
Keywords

Birds, Mice, Inbred BALB C, Virulence, Influenza A virus, Influenza in Birds, Animals, Disease Outbreaks, Russia

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
35
Top 10%
Top 10%
Top 10%
hybrid