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Translational Research
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Translational Research
Article . 2015 . Peer-reviewed
License: Elsevier TDM
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https://pubmed.ncbi.nlm.nih.go...
Article . 2015
Data sources: Europe PubMed Central
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RNA epigenetics

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2015 English Publisher:Elsevier BVJournal:Translational Research, volume 165, pages 28-35 (issn: 1931-5244, Copyright policy )
Authors: Nian, Liu; Tao, Pan;

doi: 10.1016/j.trsl.2014.04.003

pmid: 24768686

pmc: PMC4190089

RNA epigenetics

Abstract

Mammalian messenger RNA (mRNA) and long noncoding RNA (lncRNA) contain tens of thousands of posttranscriptional chemical modifications. Among these, the N(6)-methyl-adenosine (m(6)A) modification is the most abundant and can be removed by specific mammalian enzymes. m(6)A modification is recognized by families of RNA binding proteins that affect many aspects of mRNA function. mRNA/lncRNA modification represents another layer of epigenetic regulation of gene expression, analogous to DNA methylation and histone modification.

Related Organizations
Keywords

Adenosine, RNA-Binding Proteins, Methyltransferases, Epigenesis, Genetic, Translational Research, Biomedical, Mice, Animals, Humans, RNA, RNA, Long Noncoding, RNA, Messenger

  • BIP!
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    selected citations
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    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 124
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 1%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
124
Top 1%
Top 10%
Top 1%
bronze