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Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology
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Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology
Article . 2008 . Peer-reviewed
License: Elsevier TDM
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https://pubmed.ncbi.nlm.nih.go...
Article . 2009
Data sources: Europe PubMed Central
Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology
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Immunoexpression of vascular endothelial growth factor in periapical granulomas, radicular cysts, and residual radicular cysts

descriptionPublicationkeyboard_double_arrow_right Article 01 Dec 2008 Brazil Publisher:Elsevier BVJournal:Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, volume 106, pages 896-902 (issn: 1079-2104, Copyright policy )
Authors: Nonaka, Cassiano Francisco Weege; Maia, Alexandre Pinto; Nascimento, George João Ferreira do; Freitas, Roseana de Almeida; Souza, Lelia Batista de; Galvão, Hebel Cavalcanti;

doi: 10.1016/j.tripleo.2008.06.028

pmid: 18755620

Immunoexpression of vascular endothelial growth factor in periapical granulomas, radicular cysts, and residual radicular cysts

Abstract

Our aim was to assess and compare the immunoexpression of vascular endothelial growth factor (VEGF) in periapical granulomas (PGs), radicular cysts (RCs), and residual radicular cysts (RRCs), relating it to the angiogenic index and the intensity of the inflammatory infiltrate.Twenty PGs, 20 RCs, and 10 RRCs were evaluated by immunohistochemistry using anti-VEGF antibody. Angiogenic index was determined by microvessel count (MVC) using anti-von Willebrand factor antibody.The PGs and RCs showed higher expression of VEGF than the RRCs. Lesions presenting few inflammatory infiltrate revealed the lowest immunoexpression of VEGF (P .05).VEGF is present in periapical inflammatory lesions but at a lower level in RRCs. The expression of this proangiogenic factor is closely related to the intensity of the inflammatory infiltrate in these lesions.

Country
Brazil
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Keywords

Male, Vascular Endothelial Growth Factor A, Radicular Cyst, Neovascularization, Pathologic, Cyst Fluid, 610, Endothelial Growth Factors, Immunohistochemistry, Statistics, Nonparametric, Capillary Permeability, Immunoenzyme Techniques, Neutrophil Infiltration, Odontogenic Cysts, Microvessels, Humans, Female, Periapical Granuloma

  • BIP!
    Impact byBIP!
    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 35
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Average
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
35
Top 10%
Top 10%
Average
Green
bronze
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