The application of artificial intelligence (AI) in hematology it not new at all. However, it increasingly becomes part of the measurement of hematological parameters and subsequently also influences decision making. Here some examples are provided where well established parameters could be exploited better, if data are not reduced to single values but instead the entire data generation process is considered. Furthermore applications of artificial neural networks (ANN), point of care (PoC) devices and the internet of things (IoT) are discussed. Beside all the technical advancements human judgement will remain the last decision.