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Theoretical Population Biology
Article . 2006 . Peer-reviewed
License: Elsevier TDM
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Article . 2006
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https://dx.doi.org/10.48550/ar...
Article . 2005
License: arXiv Non-Exclusive Distribution
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Quasispecies and recombination

Authors: Jacobi, Martin Nilsson; Nordahl, Mats;

Quasispecies and recombination

Abstract

Recombination is introduced into Eigen's theory of quasispecies evolution. Comparing numerical simulations of the rate equations in the non-recombining and recombining cases show that recombination has a strong effect on the error threshold and, for a wide range of mutation rates, gives rise to two stable fixed points in the dynamics. This bi-stability results in the existence of two error thresholds. We prove that, under some assumptions on the fitness landscape but for general crossover probability, a fixed point localized about the sequence with superior fitness is globally stable for low mutation rates.

Related Organizations
Keywords

Recombination, Genetic, Genomics (q-bio.GN), Populations and Evolution (q-bio.PE), Recombination, Quasispecies, Problems related to evolution, FOS: Biological sciences, Crossover, Quantitative Biology - Genomics, Crossing Over, Genetic, Quantitative Biology - Populations and Evolution

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    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
36
Top 10%
Average
Average
Green
bronze