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image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Trends in Pharmacolo...arrow_drop_down
image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
Trends in Pharmacological Sciences
Article . 2024 . Peer-reviewed
License: Elsevier TDM
Data sources: Crossref
https://pubmed.ncbi.nlm.nih.go...
Article . 2024
Data sources: Europe PubMed Central
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A novel function of the M2 muscarinic receptor

descriptionPublicationkeyboard_double_arrow_right Article 01 Aug 2024 English Publisher:Elsevier BVJournal:Trends in Pharmacological Sciences, volume 45, pages 663-665 (issn: 0165-6147, Copyright policy )
Authors: Jürgen Wess; Liu Liu;

doi: 10.1016/j.tips.2024.05.010

pmid: 38853101

pmc: PMC11316642

A novel function of the M2 muscarinic receptor

Abstract

The M2 muscarinic receptor (M2R) is a prototypic class A G protein-coupled receptor (GPCR). Interestingly, Fasciani et al. recently identified an internal translation start site within the M2 receptor mRNA, directing the expression of a C-terminal receptor fragment. Elevated during cellular stress, this polypeptide localizes to mitochondria where it inhibits oxidative phosphorylation.

Related Organizations
Keywords

Receptor, Muscarinic M2, Humans, Animals, Oxidative Phosphorylation, Mitochondria

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
1
Average
Average
Average
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