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image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Trends in Pharmacolo...arrow_drop_down
image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
Trends in Pharmacological Sciences
Article . 2022 . Peer-reviewed
License: Elsevier TDM
Data sources: Crossref
https://pubmed.ncbi.nlm.nih.go...
Article . 2022
Data sources: Europe PubMed Central
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Mining LTR-retrotransposon genes for mRNA delivery

descriptionPublicationkeyboard_double_arrow_right Article 01 May 2022 English Publisher:Elsevier BVJournal:Trends in Pharmacological Sciences, volume 43, pages 355-357 (issn: 0165-6147, Copyright policy )
Authors: Marco Herrera-Barrera; Gaurav Sahay;

doi: 10.1016/j.tips.2022.01.001

pmid: 35042613

Mining LTR-retrotransposon genes for mRNA delivery

Abstract

RNA-based therapeutics commonly use exogenous components to shuttle their cargo, leading to nonselectivity or immunogenicity. Segel et al. have elucidated an endogenous modular retroviral-like delivery system capable of encapsulating mRNA, which elicits effective transport inside cells, priming the development of endogenous vectors for gene delivery for amelioration of disease.

Related Organizations
Keywords

Retroelements, Terminal Repeat Sequences, Humans, RNA, Messenger

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    popularity
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    influence
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    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
2
Average
Average
Average
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