
Anaphylaxis, a life-threatening allergic reaction, is dependent on high affinity allergen-specific IgE. Gowthaman et al. now show that a new interleukin (IL)-13-expressing T helper cell subset specifically promotes high-affinity IgE responses. The discovery of T follicular helper (Tfh)13 cells defines potential new targets for allergy therapies.
Tfh13, Interleukin-13, anaphylaxis, Humans, T-Lymphocytes, Helper-Inducer, Allergens, Immunoglobulin E, allergy, Anaphylaxis
Tfh13, Interleukin-13, anaphylaxis, Humans, T-Lymphocytes, Helper-Inducer, Allergens, Immunoglobulin E, allergy, Anaphylaxis
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